Lung-Cancer Specific T Cell Dysfunction

Methods for identifying patients susceptible to treatment with checkpoint inhibitors are provided herein. Also provided are reagents for analyzing T cell responses for understanding resistance to checkpoint inhibitor therapy and understanding therapeutics for overcoming that resistance. Therapeutic strategies, for instance, for treating cancer, are also provided.

Researchers

J. Christopher Love / Stefani Spranger / Brendan Horton / Duncan Morgan / Karl Dane Wittrup

Departments: Department of Chemical Engineering, Department of Biology
Technology Areas: Drug Discovery and Research Tools: Cell Interrogation, Cell Lines & Organoids / Therapeutics: Proteins & Antibodies
Impact Areas: Healthy Living

  • lung-cancer specific t cell dysfunction
    United States of America | Pending

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