A Multi-Pathway Reporter System that Interrogates Repair of DNA Double-Strand Breaks with Applications for Diagnosis and Therapeutic Treatment of Cancer and Neurodegenerative Diseases
Invention type: Technology
/
Case number: #25444
Researchers
Alex Kruswick
/
Michael Yaffe
Departments: Biology, Department of Biology
Technology Areas: Biotechnology: DNA & RNA Editing, Synthetic Biology / Diagnostics: Assays / Drug Discovery and Research Tools: Genomics & Proteomics
Impact Areas: Healthy Living
-
a multi-pathway reporter system that interrogates repair of dna double-strand breaks with applications for diagnosis and therapeutic treatment of canc
United States of America | Pending
Publications
Kooij, Bert van de, Alex Kruswick, Haico van Attikum, and Michael B. Yaffe. “Multi-Pathway DNA-Repair Reporters Reveal Competition between End-Joining, Single-Strand Annealing and Homologous Recombination at Cas9-Induced DNA Double-Strand Breaks.” Nature Communications 13, no. 1 (September 8, 2022). https://doi-org.ezproxyberklee.flo.org/10.1038/s41467-022-32743-w.
License this technology
Interested in this technology? Connect with our experienced licensing team to initiate the process.
Sign up for technology updates
Sign up now to receive the latest updates on cutting-edge technologies and innovations.