Oligomeric Conjugates for siRNA Delivery and Glucose-Responsive Insulins

Provided are derivatized therapeutic, prophylactic, or diagnostic agents, such as nucleic acids, that can be effectively delivered to cells and tissues. Also provided are methods of affecting a biological process by administering a therapeutic, prophylactic, or diagnostic agent, such as functional nucleic acid, to a cell or a subject, where the therapeutic, prophylactic, or diagnostic agent, such as functional nucleic acid, is derivatized therapeutic, prophylactic, or diagnostic agent, such as nucleic acid.

Researchers

Arturo Vegas / Rosemary Kanasty / Robert Langer / Daniel Anderson

Departments: Office of the Institute Professors, Department of Chemical Engineering
Technology Areas: Diagnostics: Assays / Drug Delivery: Microparticles & Nanoparticles / Therapeutics: Nucleic Acids
Impact Areas: Healthy Living

  • compositions and methods for functinal nucleic acid delivery
    United States of America | Granted | 9,970,002

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