Small Molecules Suppressors of APOE Gene Expression and Cerebral Vascular Amyloid Pathology

The present disclosure provides methods of inhibiting amyloid synthesis in a subject using small molecule inhibitors The invention also includes methods of treating disease associated with amyloid synthesis, such as Alzheimer's disease. The small molecule inhibitors disclosed herein are compounds which are non-immunosuppressant cyclosporin including the pharmaceutically acceptable salts thereof.

Researchers

Li-Huei Tsai / Joel Blanchard

Departments: DLC Heads Science
Technology Areas: Therapeutics: Small Molecules
Impact Areas: Healthy Living

  • small molecules suppressors of apoe gene expression and cerebral vascular amyloid pathology
    Patent Cooperation Treaty | Published application
  • small molecule suppressors of apoe gene expression and cerebral vascular amyloid pathology
    United States of America | Published application

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