Synthetic Cell/Condition-Specific Promoters and Enhancers
Invention type: Technology
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Case number: #18570
Synthetic promoters that are differentially modulated between certain diseased cells (e.g., cancer cells) and normal cells (e.g., non-cancer cells) are described. The synthetic promoters may be used to drive expression of gene(s) of interest in a specific cell type or during a specific cellular state. These synthetic promoters are useful, for example, for targeted expression of therapeutic molecules in diseased cells.
Researchers
Timothy K Lu
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Lior Nissim
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Ming Ru Wu
Departments: Department of Biological Engineering
Technology Areas: Biotechnology: Synthetic Biology / Therapeutics: Cell Based Therapy
Impact Areas: Healthy Living
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synthetic promoters
United States of America | Granted | 11,718,860
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