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CD80 is a Biomarker of p53 Activity and a Target for Cancer Therapy

Technology / Case number: #15386H
David Feldser / Leah Schmidt / Tyler Jacks
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Increasing Safety of Embryonic Stem Cells

Technology / Case number: #13769
Jeffrey Millman / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods for Enhanced Production of Cardiomyocytes From Embryonic Stem Cells

Technology / Case number: #12777
Daryl Powers / Jeffrey Millman / Amanda Diienno / Clark Colton
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods of Controlled Self-Renewal and Differentiation of Intestinal Stem Cells

Technology / Case number: #15728J
Jeffrey Michael Karp / Xiaolei Yin / Marc Succi / Robert Langer
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineering DNA Assembly in Vivo and Knock Down of Gene Expression Using the Reverse Transcriptase Activity

Technology / Case number: #16593
Christopher Voigt / Johann Elbaz
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Rocco Policarpo
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Microtextured and Surface Treated Soft Polymer Cell Capture and Culture Concept

Technology / Case number: #25985
Bert Joannes C Vandereydt / Sean Parks / Domitille Avalle / Laetitia Ceccoli / Kripa K Varanasi
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #12321XE
Akihiro Horii / Fabrizio Gelain / Xiumei Wang / Shuguang Zhang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Collin Martin / Himanshu Dhamankar
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Brd4 as a Prognostic Indicator and Modulator of the Cell Response to DNA Damage

Technology / Case number: #15011
Scott Floyd / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Method for the Characterization and Differentiation of Material Surfaces Using Compound Responses of Mechanically Driven Cells

Technology / Case number: #17585J
Dick Yue / Roland Bouffanais / Xiaoying Zhu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Albert Swiston / Michael F Rubner / Robert Cohen / Darrell J Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Steven Africk / Clark Colton
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Tough, Thermoreversible Hydrogels from the Arrested Phase Separation of Elastin-Like Polypeptides: Simple, Injectable, Biocompatible Substrates for the Engineering of Load-Bearing Tissues

Technology / Case number: #17430
Bradley D. Olsen / Matthew Glassman / Reginald Avery
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Genomic Editing with Site- Specific Retrotransposons

Technology / Case number: #25220
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim / Christopher Fell
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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mRNA Subunit Vaccines for African Swine Fever

Technology / Case number: #25930
Junru Cui / Fangfeng Yuan / Jianzhu Chen
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulations for Stabilizing Lactobacillus and Bifidobacterium Strains

Technology / Case number: #25723J
Giovanni Traverso / Christina Karavasili / Matt Murphy / Samantha Bozorgzadeh / Mairead Heavey / Kimberley Biggs / Isaac Tucker
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Jong Ho Kim / Paul Barone / Jin Ho Ahn / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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A Synthetic Nanotube Antibody for Selective Molecular Recognition

Technology / Case number: #14090
Michael S. Strano / Jong Ho Kim / Paul Barone / Daniel Heller / Jingqing Zhang
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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