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SpongeBot: Programmable Solution Providing Unmatched Protection Against Pandemics

Technology / Case number: #22349J
Ron Weiss / Jin Huh / Yingzhong Li / Hava Siegelmann / Eric Goldstein
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Two Person Mixture Deconvolution for Application with ForenSeq Kintelligence Workflow

Technology / Case number: #24078L
Philip Fremont-Smith / Chelsea Lennartz / Natalie Damaso
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Optimized Opsin Trafficking with Fluorescence-Dead Protein Fusions

Technology / Case number: #18783TE
Edward Stuart Boyden / Kiryl Piatkevich / Aimei Yang / Demian Park
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Dynamic Single-Cell Fragility Test that Assesses Red Blood Cell Membrane Integrity with Applications to Stored Blood

Technology / Case number: #25732J
Fang Kong / Subra Suresh / Ming Dao
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Method to Pattern Cells (Crude Blood) on a (Planar) Surface

Technology / Case number: #15262
Shivang Dave / German Serrano
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Long-term Stabilization, Formulation and Tableting of Live Microbial Cells

Technology / Case number: #22886J
Giovanni Traverso / Robert Langer / Miguel Jimenez / Johanna L'Heureux / Emily Kolaya
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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In Vitro Human Blood Brain Barrier

Technology / Case number: #19918P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for Improving Cross-Ancestry Transferability in Predicting Polygenic Phenotypes from Genetic Variation

Technology / Case number: #24858
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Novel Peptides Capable of Altering NK Cell Activity

Technology / Case number: #24321JQ
Michael Birnbaum / Brooke Huisman / Chiara Romagnani / Timo Ruckert
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matt Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Computationally-Optimized ACE2 Peptides for Competitive Interception of SARS-CoV-2

Technology / Case number: #22320XTE
Pranam Chatterjee / Raghava Manvith Ponnapati / Eyal Perry / Joseph Jacobson
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Zero-Crossing-Based Bio Engineered Sensor

Technology / Case number: #23713J
Timothy K Lu / Giovanni Traverso / Phillip Nadeau / Christoph Winfried Johannes Steiger / Rabia Yazicigil Kirby / Maria Eugenia Inda / Miguel Jimenez / Adam Wentworth / Jenna Ahn / Qijun Liu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Methods of Enhancing the Survival of Introduced Genes and Organisms

Technology / Case number: #22105TE
Kevin Esvelt / Sarah Vitak
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Robert Langer / Ganesh Shankar
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
D.B.Jay Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diagnosis of Malignancy Using Developmental Relationships and Machine Learning

Technology / Case number: #23356
Salil Garg / Enrico Moiso
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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