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Continuous Flow Lithography

New
Technology / Case number: #11917
Patrick Doyle / Daniel Pregibon / Dhananjay Dendukuri / T. Alan Hatton
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

New
Technology / Case number: #26051J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Avik Som / Jan-Georg Rosenboom / Eric Wehrenberg-Klee / Stephen Linderman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Flexible Phase-Transitioning Needles for Shear Stress Reduction

New
Technology / Case number: #24651J
Giovanni Traverso / Young-Geun Park
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Development of Red to NIR Luminescent Carbodicarbene-Borabenzo[c]anthanthrenium Ions

New
Technology / Case number: #26386
Robert Gilliard / Chunlin Deng / Bi Youan Eric Tra
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Self-Righting Systems, Methods, and Related Components

New
Technology / Case number: #20706JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
License

AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Utilizing a Strategic Blend of Block Copolymers to Control Particle Surface Charge for Enhanced Mucus Transport and Tissue Targeting

Technology / Case number: #25439J
Katharina Ribbeck / Corey Alfred Stevens / Robert Prud'homme / Boris Sevarika / Brian Wilson / Angela Belcher
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
License

Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Yuting Huang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Kamat / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Colloidal Hydrogel Particles with tunable Chemistry, Geometry, and Flexibility

Technology / Case number: #13461J
Patrick Doyle / Daniel Pregibon / Ramin Haghgooie / Mehmet Toner
Technology Areas: Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
License

Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
License

A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Ameya Kirtane / Ming Zhao / Troy Ziliang Kang / Yubin Cai
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Scaffold System for Microfluidic Tissue Chips

Technology / Case number: #25885
Linda Griffith / Priyatanu Roy / Matthew Johnson / David L Trumper
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
License

Strategy for Installing Hydrophobic Chains Plus Phosphorus Ligands onto MOFs

Technology / Case number: #25160
Mircea Dinca / Valiallah Hosseininasab / Nathan Gin
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
License

Lipid Compositions and Methods

Technology / Case number: #25115J
Sho Toyonaga / Theresa Raimondo / Dennis Shi / Daniel Anderson
Technology Areas: Drug Delivery
Impact Areas: Healthy Living
License

A Single Fibre Computer Enables Textile Networks and Distributed Inference

Technology / Case number: #26084
Zi Jie Gabriel Loke / Henry Cheung / Nikhil Gupta / Syamantak Payra / Yoel Fink
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Connected World
License

Synergisms between Small Molecule Boosters and LNP Formulations Uncovered using High Throughput Screening and Machine Learning

Technology / Case number: #26199J
Giovanni Traverso / Ameya Kirtane / Rajib Dey / Deepak Subramanian
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

LNP Automation Screening System

Technology / Case number: #26217
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Xin Yang / Zhiling Zheng
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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