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A Mechanical Underwater Soft Adhesion System for Kinetic Biosensing and Intelligent Targeted Drug Delivery

Technology / Case number: #26028J
Giovanni Traverso / Ameya Kirtane / Ming Zhao / Troy Ziliang Kang / Yubin Cai
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lithium-Ion Fiber Battery

Technology / Case number: #16676
Benjamin Grena / Yoel Fink
Technology Areas: Chemicals & Materials / Drug Delivery / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Deepak Dugar / Brian Pereira / Marjan De Mey / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Zwitterionic Dopamine Sulfonate Coated Iron Oxide Nanoparticles

Technology / Case number: #15322
Numpon Insin / Hee-Sun Han / He Wei / Moungi G Bawendi
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Injectable Hydrogel and Uses Thereof

Technology / Case number: #16662J
Yizhou Dong / Benjamin Tang / Kun Xue / Matthew Webber / Omid Veiseh / Weiheng Wang / Eric Appel / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Mark Bathe / Grant Knappe / Anna Romanov / Darrell J Irvine
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Controlled Assembly of Lipid-Based Nanoparticles from Surfactant Micelles

Technology / Case number: #25418H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Joseph Gardecki / Matthew Johnson / Osman Ahsen / Michael Bradshaw / Guillermo Tearney
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Ionizable Lipid OF-02 and its Use in mRNA Delivery

Technology / Case number: #17733
Joseph Dorkin / Owen Fenton / Kevin Kauffman / Rebecca McClellan / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Frameshift Suppressor tRNAs for Canonical Amino Acids

Technology / Case number: #21418TREJ
Kevin Esvelt / Erika Alden DeBenedictis / Ahmed Badran
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Tunable Structure of Biodegradable Silk-Based Microcapsules for Soluble and Insoluble Payload Delivery

Technology / Case number: #23764J
Benedetto Marelli / Muchun Liu / Pierre-Eric Millard / Henning Urch / Ophelie Zeyons / Rupert Konradi / Bernd Oschmann / Yagmur Yegin
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Dissolvable Microcarriers for Adherent Cell Culture

Technology / Case number: #22052JDE
Ee Xien Ng / Krystyn Van Vliet
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Oleogel Drug Delivery Systems for Pediatric Applications

Technology / Case number: #22116J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Aniket Wahane / Christina Karavasili
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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