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Injectable, Thermogelling, Prolonged-Release Hydrogel Formulations for CPG-ODNs

New
Technology / Case number: #26051J
Giovanni Traverso / Ameya Kirtane / Robert Langer / Avik Som / Jan-Georg Rosenboom / Eric Wehrenberg-Klee / Stephen Linderman
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Acid-Gas Regeneration Process for Ex-Situ Carbon Mineralization of Magnesium Silicate Minerals

New
Technology / Case number: #26097
Yogesh Surendranath / Anatole Borisov
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future, Advanced Materials
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Fluidic-Based Cell Capture and Adhesion Measurement Concept

New
Technology / Case number: #25888
Bert Joannes C Vandereydt / Sean Parks / Domitille Avalle / Kripa K Varanasi
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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A Double Pinch Criterion for Optimization of Regenerative Rankine Cycles: Powerplant Operation and Simmulation/Optimization Software Modeling Strategies

New
Technology, Software / Case number: #14875
Alexander Mitsos / Hussam Zebian
Technology Areas: Energy & Distribution / Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Climate Stabilization, Sustainable Future
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N-Heterocyclic Imine as a Potential Redox-Active Sorbent for Electrochemical CO2 Separation

New
Technology / Case number: #26251
Betar Gallant / Fang-Yu Kuo / Glen Junor / Akachukwu Obi
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Decoupling CO2 Capture and Electrochemical Sorbent Regeneration with Nanofiltration

New
Technology / Case number: #26244
Simon Rufer / Tal Joseph / Zara Aamer / Kripa K Varanasi
Technology Areas: Energy & Distribution / Environmental Engineering / Sensing & Imaging
Impact Areas: Climate Stabilization, Sustainable Future
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mRNA-based Myeloid Cell Stimulation Enhances Therapeutic Efficacy

New
Technology / Case number: #25731J
Ralph Weissleder / Akash Gupta / Kaelan Reed / Riddha Das / Christopher Garris / Daniel Anderson
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods, Materials, and Systems for Valorization of Gypsum and Phosphogypsum based Feedstocks

New
Technology / Case number: #26410
Camden Hunt / Amilton Botelho Junior / Yet-Ming Chiang
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Intermediate Temperature Steam Electrolysis In a Molten Salt Electrolyte

New
Technology / Case number: #26155
Yogesh Surendranath / Rui Zeng / India Cox
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future, Advanced Materials
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Self-Righting Systems, Methods, and Related Components

New
Technology / Case number: #20706JQ
Giovanni Traverso / Taylor Bensel / Alex Abramson / Minsoo Khang / Niclas Roxhed / Ester Caffarel Salvador / Robert Langer
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Methods, Procedures, and Material Compositions to Formulate Thermally Stable Solid-State Lipid Nanoparticles via Drying at Ambient Conditions

Technology / Case number: #26177
Ana Jaklenec / Robert Langer / Mina Konakovic Lukovic / Jinbi Tian / Khanh Tran / Amy Lee
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Altered DNA Repair Pathway Engagement by Engineered CRISPR-Cas9 Nucleases

Technology / Case number: #23588
Vikash Pal Singh Chauhan / Robert Langer / Phillip Sharp
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Poly(-amino ester) Microparticles for Micronutrient Fortification

Technology / Case number: #22992
Ana Jaklenec / Robert Langer / Ruiqing Xiao / Linzixuan Rhoda Zhang
Technology Areas: Agriculture & Food / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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AO mRNA-LNP Stabilization

Technology / Case number: #26266
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Jooli Han / Tina Huang
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Plk1 inhibitor and Microtubule Poison Dual Payload Antibody Drug Conjugates for the Treatment of Cancer

Technology / Case number: #26136
Jesse C Patterson / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Lipid-Polymer Microparticles (mLPM) For Thermostable, Pulsatile mRNA-LNP Vaccines

Technology / Case number: #26154
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Yuting Huang
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Branched Poly(-amino esters) for the Delivery of Nucleic Acids

Technology / Case number: #20333JQ
Giovanni Traverso / Yunhua Shi / Ameya Kirtane / Grace Junyue Zhong / Daniel Reker / Robert Langer / Hyunjoon Kim / Netra Kamat / James Byrne / Gary Liu
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Methods for Microbial Oil Overproduction from Cellulosic Materials

Technology / Case number: #15695
Mitchell Tai / Gregory Stephanopoulos
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Healthy Living, Sustainable Future
License

Expression Constructs for One-Step Construction of Allogeneic CAR-NK Cells

Technology, Tangible Property / Case number: #26118J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Connected World
License

Methods for Improving Statistical Power in Genetic Discovery by Incorporating Quality Control Flags

Technology / Case number: #25839P
Manolis Kellis / Yosuke Tanigawa
Technology Areas: Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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