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In Vitro Human Blood Brain Barrier

Technology / Case number: #19918P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Methods for the Treatment of Trinucleotide Repeat Expansion Disorders Associated with FAN1 activity via Targeting of FAN1 Splice Site Inhibitory Sequences

Technology / Case number: #24829
Christopher Ng / David Housman
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Vibrating Ingestible BioElectronic Stimulator (VIBES)

Technology / Case number: #23759JQ
Giovanni Traverso / Shriya Sruthi Srinivasan / Robert Langer / Amro Alshareef
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Novel Peptides Capable of Altering NK Cell Activity

Technology / Case number: #24321JQ
Michael Birnbaum / Brooke Huisman / Chiara Romagnani / Timo Ruckert
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Transforming Silicate Containing Materials into Reactive Materials for CO2 Capture and Other Applications

Technology / Case number: #24493J
Matthew Kanan / Yogesh Surendranath / Wei Lun Toh / Rishi Agarwal / Benjamin Charnay / Yuxuan Chen / Joshua Rabinowitz
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future
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Bioelectronic Devices to Support Transplanted Cells in Vivo for Encapsulated Cell Therapies

Technology / Case number: #23269J
Suman Bose / Robert Langer / Siddharth Krishnan / Matt Bochenek / Nima Khatib / Daniel Anderson
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living
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Maximizing Carbon Efficiency in CO2 Electrolyzers: Complete Conversion of Bicarbonate to Formate

Technology / Case number: #24910
Ju Li / Zhen Zhang / Zhichu Ren
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Curbside-recyclable Products from Mono-material Polyethylene Fabrics With Polyethylene 3D Printed Features and Methods Thereof

Technology / Case number: #24436
Svetlana V Boriskina / Volodymyr Korolovych / Leslie Yan / Duo Xu
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Reconfigurable Precast Concrete Construction System for Buildings Designed through Algorithmic Engineering with Inventory Constraints

Technology / Case number: #25018
Caitlin T Mueller / Inge Donovan / Jenna Schnitzler / Keith Lee / Yanjun Liu / Pitipat Wongsittikan
Technology Areas: Environmental Engineering / Industrial Engineering & Automation
Impact Areas: Sustainable Future
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Composite Anti-Fouling Coatings Designed via Full Spectral Hamaker Constant Minimization

Technology / Case number: #21606J
Michael Short / Max Carlson / Robert Simpson
Technology Areas: Chemicals & Materials / Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Noise Recycling

Technology / Case number: #22102J
Kenneth Duffy / Amit Solomon / Alejandro Cohen / Muriel Medard
Technology Areas: Communication Systems / Computer Science / Environmental Engineering
Impact Areas: Sustainable Future, Connected World
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Determining Phosphate Levels in Natural Water Using a Novel Electrochemical Measurement Device

Technology / Case number: #21708
Gee Hoon Park / Ian Hunter
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Robert Langer / Ganesh Shankar
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
D.B.Jay Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Receptor Specific Peptides for Bcl-2 Family Anti-apoptotic Proteins

Technology / Case number: #20337J
Amy Keating / Gevorg Grigoryan / Justin Jenson / Vincent Xue / Jianfu Zhou
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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