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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Stephen Goldfless / Jacquin Niles / Michael Marletta
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Dendrimer and Peptide Based Excipients for the Attenuation of Protein Aggregation

Technology / Case number: #14184
Curtiss Schneider / Diwakar Shukla / Bernhardt Trout
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Therapeutics
Impact Areas: Healthy Living
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Mark Bathe / Grant Knappe / Anna Romanov / Darrell J Irvine
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Yin Ren / Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Yin Hao Chang / Sylvain Ladame / Dana Al Sulaiman / Darrell J Irvine
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Mohammad Rashidian / Jennifer Rowley / Taha Rakhshandehroo / Ali Salehi / Julia Froese
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Pulsing Light to Promote Recovery from Amblyopia

Technology / Case number: #25767P
Mark Bear / Francis Reilly-Andujar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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High-Recovery, Reliable Electrodialysis for Household Desalination

Technology / Case number: #25718
Amos Winter / Ben Judge / Michael Bono / Jeffrey Costello / Jonathan Bessette / Melissa Brei / Emily Welsh / Antonia Filingeri / Giuliana Pertuz / Sophia Chen
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Sustainable Future
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Scalable Biomass-Derived Hydrogels for Sustainable Carbon Dioxide Capture

Technology / Case number: #25513
T. Alan Hatton / Youhong (Nancy) Guo
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Ozgun Kocabiyik / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Renewable Bio-Advantaged Plasticizer Generated by Reductive Coupling of Lignin Derived Aromatics

Technology / Case number: #25385J
Yuriy Roman / Gregg Beckham / Shannon Stahl / Jack Twilton / Caroline Hoyt / Zhiming Su
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Lipase-Expressing E. Coli

Technology, Tangible Property / Case number: #25403
Ariel Furst / Gang Fan / Barathkumar Baskaran
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Max Cotler / Hannah Jackson / Cameron Metcalf / Karen Wilcox / Peter West
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Adam Marblestone / Samuel Rodriques / Nicholas Barry
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Breanna DiAndreth / Noreen Wauford
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Nanoengineered Hierarchical Polysulfone Membrane for Emulsion Separation

Technology / Case number: #15286
Nasim Hyder / Brian Solomon / Kripa K Varanasi
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization
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A Therapeutic Strategy for Rett Syndrome and Autism Spectrum Disorders

Technology / Case number: #12720WPJ
Daniela Tropea / Emanuela Giacometti / Rudolf Jaenisch / Mriganka Sur / Nathan Wilson
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Kannan Tharakaraman / Vidya Subramanian / Devin Quinlan / Ram Sasisekharan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Design of High Recovery and High Salt Removal Electrodialysis Stack for Household Applications

Technology / Case number: #25851
Amos Winter / Melissa Brei
Technology Areas: Energy & Distribution / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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  • Water Desalination
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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