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High-Throughput Untranslated Region Engineering and Screening

Technology / Case number: #19123
Timothy K Lu / Manolis Kellis / Jicong Cao / Eva Maria Novoa Pardo / Zhizhuo Zhang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Recombinase-Based Genetic Diversification Schemes

Technology / Case number: #18173
Timothy K Lu / Sara Da Luz Areosa Cleto
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Syncells - Artificial Colloidal Folded 2d Electronic State-Machines - Fabrication and Applications

Technology / Case number: #19030
Michael S. Strano / Tianxiang Liu / Pingwei Liu / Daichi Kozawa / Volodymyr Koman
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Healthy Living, Connected World
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Method to Distinguish and Analyze White Blood Cells in the Presence of Red Blood Cells

Technology / Case number: #18889
Shivang Dave / Jason Tucker-Schwartz
Technology Areas: Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Electromechanical Lysis of Bacterial Pathogens using Ion Concentration Polarization

Technology / Case number: #19035
Minseok Kim / Jongyoon Han
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Efficient Smith-Purcell Radiation Sources and Enhancement Methods

Technology / Case number: #19456
Steven Earl Kooi / Ido Efraim Kaminer / Nicholas Rivera / Yi Yang / Tena Dubcek Varga / Aviram Massuda / Charles Roques-Carmes / Yujia Yang / John D Joannopoulos / Marin Soljacic / Karl Berggren
Technology Areas: Electronics & Photonics / Environmental Engineering / Sensing & Imaging
Impact Areas: Advanced Materials
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Atherofluidics-on-Chip

Technology / Case number: #18096
Sarvesh Varma / Joel Voldman
Technology Areas: Drug Discovery and Research Tools
Impact Areas: Healthy Living
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M13 Phage Assembly System for Optimal Blood Trafficking, Tumor Penetration, and Passage Across the Blood Brain Barrier

Technology / Case number: #19438
Uyanga Tsedev / Fred Lam / Angela Belcher
Technology Areas: Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Compositions and Methods for Treating and Preventing Obesity

Technology / Case number: #18085J
Manolis Kellis / Melina Claussnitzer / Jan Korbel
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Multiplexed Specific Metalloprotease Activity Measurements

Technology / Case number: #19425DE
Miles Miller / Caroline Chopko Ahrens / Christi Cook / Steven Robert Tannenbaum / Ravindra Kodihalli / Evan Chiswick / Linda Griffith / Douglas Lauffenburger
Technology Areas: Biomaterials & Bioelectronics / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Open-Ended, Dicer-Cleavable Concatemeric siRNA Generated by Rolling Circle Transcription

Technology / Case number: #18076
Connie Wu / Kevin Shopsowitz / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Development of Multi-Specific Antibody-Serum Albumin Fusion Proteins Targeting Multiple Human and Murine CXC (ELR+) Chemokines

Technology / Case number: #19355JQ
Alessandro Angelini / Andrew Luster / Karl Dane Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Delivery of Preassembled Double-Stranded Short Interference RNA-Argonaute Protein Complexes for Enhanced RNAi-Based Therapeutics

Technology / Case number: #19340
Jiahe Li / Yanpu He / Wade Wang / Paula Hammond
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Uncharted Frontiers
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A Biomedical Imaging and Optical Stimulation Device

Technology / Case number: #18022
Juejun Hu / Tian Gu / Qi Qin
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
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METRAN - Software for 13C-metabolic Flux Analysis

Software / Case number: #12397
Technology Areas: Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Connected World
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Structured DNA Conjugates

Technology / Case number: #18588
Mark Bathe / Sakul Ratanalert / Remi Veneziano / Tyson Shepherd / Hyungmin Jun
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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N/ASynergistic Tumor Treatment with IL-2, an Integrin-Binding-FC Fusion Protein, and a Cancer Vaccine

Technology / Case number: #18598HJ
Byron Kwan / Cary Opel / Kelly Moynihan / Darrell J Irvine / Jennifer Cochran / Karl Dane Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High Molecular Weight, Post-Translationally Modified Proteins Brushes Through Tyrosine Modification Chemistry

Technology / Case number: #17927
Bradley D. Olsen / Brian Seifried
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Engineered Multifunctional Particles for Enhanced Oil Recovery

Technology / Case number: #17892
Nurxat (Nuerxiati) Nuraje (Nueraji) / Yu Lei / Hiroshi Atsumi / Xunpei Liu / Angela Belcher
Technology Areas: Chemicals & Materials / Energy & Distribution / Sensing & Imaging
Impact Areas: Climate Stabilization, Sustainable Future
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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