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Synthesis and Anticancer Activity of Epipolythiodiketopiperazine Alkaloids

Technology / Case number: #16016J
Mo Movassaghi / Nicolas Boyer / Justin Kim / Paul Hergenrother / Karen Morrison
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Inhalable Nanosensors with Volatile Reporters for Rapid Pathogen Identification in Respiratory Infections

Technology / Case number: #20307HL
Leslie Chan / Melodi Anahtar / Rod Kunz / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Multilayer Porous Hydrogel for Robust Sensing of Macromolecules with Florescent Carbon Nanotube Sensors

Technology / Case number: #15892
Michael S. Strano / Nigel Reuel
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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Develop New Lethal Mutagens for Viral Diseases

Technology / Case number: #16089
John M Essigmann / Deyu Li / Katherine Silvestre
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Genomic Insertion of Large Cargo with Engineered Retro Elements

Technology / Case number: #23248
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ligand-Inducible Post-Transcriptional Gene Regulation Using Protein-Binding RNA Aptamers

Technology / Case number: #13998J
Brian Belmont / Stephen Goldfless / Jacquin Niles / Michael Marletta
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The Design of DNA-scaffolded Subunit Vaccines for Enhanced Germinal Center Responses in HIV Vaccination

Technology / Case number: #25982H
Mark Bathe / Grant Knappe / Anna Romanov / Darrell J Irvine
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Advanced Materials
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High-Throughput Corrosion Testing Platform

Technology / Case number: #16470
Matthew Whitfield / Krystyn Van Vliet
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
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Peptide Nucleic Acid Functionalized Hydrogel Microneedles for Sampling and Detection of Interstitial Fluid Nucleic Acids

Technology / Case number: #21359HJ
Yin Hao Chang / Sylvain Ladame / Dana Al Sulaiman / Darrell J Irvine
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Cancer Therapeutics through Brain Stimulation

Technology / Case number: #25655TE
Deblina Sarkar / Ishaq Khan / Ray Lee / Monochura Saha
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Applications of Streptococcus-derived Cas9 Nucleases on Minimal A-Rich PAM Targets

Technology / Case number: #20491XTE
Noah Jakimo / Lisa Nip / Pranam Chatterjee / Joseph Jacobson
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Controlled Assembly of Lipid-Based Nanoparticles from Surfactant Micelles

Technology / Case number: #25418H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Development of a Platform to Noninvasively Image Car T Cells

Technology / Case number: #25905J
Michael Hemann / Mohammad Rashidian / Jennifer Rowley / Taha Rakhshandehroo / Ali Salehi / Julia Froese
Technology Areas: Biotechnology / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Full-field Optical Coherence Microscopy System Using a Digital Focal Plane Array

Technology / Case number: #24144LJ
Joseph Gardecki / Matthew Johnson / Osman Ahsen / Michael Bradshaw / Guillermo Tearney
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living, Advanced Materials
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Pulsing Light to Promote Recovery from Amblyopia

Technology / Case number: #25767P
Mark Bear / Francis Reilly-Andujar
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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System and Method to Predict Exertional Heat Stroke from Torso-Worn Sensor

Technology / Case number: #21970LJ
Jeffrey Palmer / Brian Telfer / Jim Williamson / Lara Weed / Mark Buller / Rebecca Fellin / Joseph Seay
Technology Areas: Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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One-Step Construction of Allogeneic CAR-NK Cells with Increased Anti-Tumor Cytotoxicity and Resistant to Rejection by Host T Cells and NK Cells

Technology / Case number: #25757J
Rizwan Romee / Fuguo Liu / Jianzhu Chen
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Scalable Biomass-Derived Hydrogels for Sustainable Carbon Dioxide Capture

Technology / Case number: #25513
T. Alan Hatton / Youhong (Nancy) Guo
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Sustainable Future
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Renewable Bio-Advantaged Plasticizer Generated by Reductive Coupling of Lignin Derived Aromatics

Technology / Case number: #25385J
Yuriy Roman / Gregg Beckham / Shannon Stahl / Jack Twilton / Caroline Hoyt / Zhiming Su
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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