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COMPOSITIONS OF POLYHYDROXYLATED BENZOPHENONES AND METHODS OF TREATMENT OF NEURODEGENERATIVE DISORDERS

Technology / Case number: #17855PJQ
Li-Huei Tsai / Stephen Haggarty / Debasis Patnaik / Ping-Chieh Pao
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Compositions of Polypeptides for Subunit Vaccines for SARS-CoV-2

Technology / Case number: #22703
J. Christopher Love / Neil Dalvie / Sergio Rodriguez
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Novel Peptides to Inhibit Ena/VASP Proteins

Technology / Case number: #22897J
Amy Keating / Theresa Hwang / Meucci IIunga / Sara Parker / Ghassan Mouneimne / Samantha Hill
Technology Areas: Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Synthesis of Potent Epidithiodiketopiperazines Designed for Facile Derivatization

Technology / Case number: #21469
Mo Movassaghi / Joshua Payette / Jaime Cheah / Chase Olsson / Tony Scott
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Intranasal amphiphile-protein conjugate vaccine

Technology / Case number: #23991H
Brittany Hartwell / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Universal Redirection of Chimeric Antigen Receptor T Cells Against Solid Tumors via Tumor Cell Membrane-Inserting CAR Ligands

Technology / Case number: #24270H
Angela Zhang / Laura Chen / Alexander Hostetler / Darrell J Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Methods for Machine-Learning Guided Protein Design

Technology / Case number: #25084
Omar Abudayyeh / Jonathan S. Gootenberg / Kaiyi Jiang / Matteo Di Bernardo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Molecular Time Capsules Enable Transcriptomic Recording in Living Cells

Technology / Case number: #25337
Gene-Wei Li / Mirae Parker / Jack Rubien / Dylan McCormick
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Augmentation of T and B Cell Activation with a Novel Cysteine Protease Linker Sequence

Technology / Case number: #25338
Sean-Luc Shanahan / Tyler Jacks
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Machine Learning-guided Whole-Organ Optical Imaging Technique for Non-destructive Identification of Early Pre-Cancer Lesions and Harvesting of Viable Cells from the same for Organoid Culture

Technology / Case number: #25480
Neelkanth Manoj Bardhan / Vivek Rastogi / Angela Belcher
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Electronics & Photonics / Sensing & Imaging
Impact Areas: Healthy Living
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An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley L. Pentelute / Andrei Loas / Jacob Rodriguez / Heemal Dhanjee / Aurelie Rondon / Katsushi Kitahara
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Medical Recordkeeping Microneedles

Technology / Case number: #24923
Ana Jaklenec / Robert Langer / Maria Kanelli / Jooli Han / Yang Liu / Fredo Durand (he/him/his)
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Non-Invasive Tactile Stimulation for Improving Motor Function

Technology / Case number: #22928P
Li-Huei Tsai / Ho-Jun Suk / Guojie Xu / Arit Banerjee
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Lectin Fingerprinting for Mapping Viral Glycosylation and Identifying Neutralizing Antibodies

Technology / Case number: #22955
Laura L Kiessling / Michael Wuo / Amanda Dugan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Tunable Phosphorylation-based Feedback Controller of Mammalian Gene Expression

Technology / Case number: #22932
Ron Weiss / Ross Jones / Domitilla Del Vecchio / Yili Qian
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Single-Cell Density as A Biomarker for Drug Sensitivity

Technology / Case number: #23741J
Keith Ligon / Weida Wu / Teemu Miettinen / Sarah Ishamuddin / Kin-Hoe Chow / Scott Manalis
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Improved Treatment for Organ Regeneration and Blocking Scar Formation

Technology / Case number: #25302
Ioannis Yannas
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Overcoming Emission Photon Scattering in Wide-Field Microscopy

Technology / Case number: #20164P
Christopher Rowlands / Jong Kang Park / Yi Xue / Kalen Berry / Balpreet Ahluwalia / Dushan Wadduwage / Peter So / Elly Nedivi
Technology Areas: Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Advanced Architectures and Operating Principles for Electrochemical Neuro-Modulation

Technology / Case number: #20280J
Daniel Freeman / Matthew Flavin / Jongyoon Han
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
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A Multimodal Metric for Tracking Nociception Under Anesthesia

Technology / Case number: #20522J
Emery N Brown / Riccardo Barbieri / Sandya Subramanian
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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