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FISHTALE- Fluorescent In Situ Hybridization of TAL Effectors

Technology / Case number: #19813TE
Edward Stuart Boyden / Adam Marblestone / Samuel Rodriques / Nicholas Barry
Technology Areas: Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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RNA Degradation-based Toggle Switch

Technology / Case number: #21622
Ron Weiss / Breanna DiAndreth / Noreen Wauford
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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A Therapeutic Strategy for Rett Syndrome and Autism Spectrum Disorders

Technology / Case number: #12720WPJ
Daniela Tropea / Emanuela Giacometti / Rudolf Jaenisch / Mriganka Sur / Nathan Wilson
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Anti-Ebola Neutralizing Antibodies

Technology / Case number: #17334
Kannan Tharakaraman / Vidya Subramanian / Devin Quinlan / Ram Sasisekharan
Technology Areas: Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Artificially Engineered Protein Hydrogels to Mimic Nucleoporin Selective Gating

Technology / Case number: #17166
Bradley D. Olsen / Minkyu Kim
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Combined 40Hz Stimulation and Dexmedetomidine Therapy for Alzheimers Disease and Neuronal Degeneration

Technology / Case number: #25176PJ
Li-Huei Tsai / Emery N Brown / Diane Chan / Jordan Harrod / Oluwaseun Johnson-Akeju
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Zwitterionic Polymer Functionalized Lipid Nanoparticles for Delivery of mRNA

Technology / Case number: #24662
Robert Langer / Allen Jiang / Sushil Lathwal / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Robocap

Technology / Case number: #24836J
Giovanni Traverso / Shriya Sruthi Srinivasan / Robert Langer / Amro Alshareef
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Modular MicroRNA Expression from Self-Replicating RNA (Replicons)

Technology / Case number: #25464
Ron Weiss / Tea Crnkovic
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Boron-Containing Pharmacophore

Technology / Case number: #21111
Ronald T Raines / Ian Windsor / Brian Graham
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Compositions for Protein Labeling Using Lipoic Acid Ligases

Technology / Case number: #15299J
Daniel Liu / Lucas Nivon / Florian Richter / David Baker / Alice Ting
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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DIAL: Programmable Promoter Editing to Generate Defined, Heritable Setpoints of Gene Expression

Technology / Case number: #25874
Katie Galloway / Sneha Kabaria / Yunbeen Bae
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Peptide-Targeted Layer-by-Layer Nanoparticle for Glioblastoma Treatment

Technology / Case number: #25659
Natalie Boehnke / Nicholas Lamson / Andrew Pickering / Priya Ganesh / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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Conformable Ultrasound Face Patch for Cavitation Enhanced Transdermal

Technology / Case number: #24824TE
Canan Dagdeviren
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Enhanced Differentiation to Endodermal Derivatives with Modulated Oxygen Level

Technology / Case number: #15589
Jeffrey Millman / Amanda Diienno / Clark Colton
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Fusion Proteins As A Cause For ALS

Technology / Case number: #24280J
Ernest Fraenkel / Ghazaleh Sadri-Vakili / Sali Farhan / Yogindra Raghav / Vakili Khashayar / Tiziana Petrozziello / James Berry / Merit Cudkowicz / Spencer Kim / Allison Dilliott / Michael Talkowski / Dadi Gao / Ricardo Pinto
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Phosphorylation-Based miRNA High Sensor

Technology / Case number: #19683
Ron Weiss / Jin Huh / Ross Jones
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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A Signal Inverter Module for RNA Cleavers: Detecting and Evaluating miRNA, Ribozymes, and Ribonucleases

Technology / Case number: #19604
Ron Weiss / Breanna DiAndreth
Technology Areas: Biotechnology / Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

New Genetic Circuit Topologies for High Performance Multi-Input MicroRNA Sensors for Classifying Living Cell State

Technology / Case number: #19534
Ron Weiss / Jin Huh
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Computational Reconfigurable Imaging Spectrometer (CRISP)

Technology / Case number: #19426L
Charles Wynn / Yaron Rachlin / Adam Milstein / Ryan Sullenberger / Sumanth Kaushik
Technology Areas: Agriculture & Food / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living, Sustainable Future
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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