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Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Polymer Brush-Poly(glycoamidoamine)-Lipids (PGAL) and Uses Thereof

Technology / Case number: #15942
Yizhou Dong / Joseph Dorkin / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Vaccine Nanotechnology and Uses Thereof

Technology / Case number: #12788J
Frank Alexis / Liangfang Zhang / Pamela Basto / Ulrich Von Andrian / Tobias Junt / Elliot Moseman / Matteo Iannacone / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Zwitterionic Dopamine Sulfonate Coated Iron Oxide Nanoparticles

Technology / Case number: #15322
Numpon Insin / Hee-Sun Han / He Wei / Moungi G Bawendi
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Healthy Living, Advanced Materials
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Method for High Efficiency in Vivo Gene Editing

Technology / Case number: #17117H
Wen Xue / Joseph Dorkin / Hao Yin / Tyler Jacks / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Method for Modulating the Immune System Using Adjuvant-Loaded Nanoparticle-Bacteria Constructs

Technology / Case number: #16067J
Michael Starnbach / Aleksandar Radovic-Moreno / Pamela Basto / Ulrich Von Andrian / Georg Stary / Robert Langer / Omid Farokhzad
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Nanoparticle Delivery of Adjuvant-Method of Preparation and Uses Thereof

Technology / Case number: #13344J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Thiol-yne Mediated Synthesis of Multi-Tailed Lipids for siRNA Delivery

Technology / Case number: #15846
Kevin Love / Akinleye Alabi / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Injectable Hydrogel and Uses Thereof

Technology / Case number: #16662J
Yizhou Dong / Benjamin Tang / Kun Xue / Matthew Webber / Omid Veiseh / Weiheng Wang / Eric Appel / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Reversible Covalent Modification for Improving Protein Delivery

Technology / Case number: #16581HQ
Li Tang / Darrell J Irvine
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Self-Assembled (Poly-(L-Glutamic Acid-PEG-Drug)-PLGA Micelles for Multistage Nanoparticle Delivery System

Technology / Case number: #14877J
Cliff Wong / Dai Fukumura / Moungi G Bawendi / Rakesh K. Jain
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Tissue Specific Delivery of Interfering RNA

Technology / Case number: #13947H
Yin Ren / Sangeeta Bhatia
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Controlled Assembly of Lipid-Based Nanoparticles from Surfactant Micelles

Technology / Case number: #25418H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Vaccine Targeting to Mucosal Lymphoid Tissues in the Gastrointestinal Tract

Technology / Case number: #25463H
Ozgun Kocabiyik / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Micro-Invasive Neural System for Delivering Antiseizure Medications to the Epileptic Focus for the Treatment of Refractory Epilepsy

Technology / Case number: #25721J
Michael Cima / Max Cotler / Hannah Jackson / Cameron Metcalf / Karen Wilcox / Peter West
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
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Zwitterionic Polymer Functionalized Lipid Nanoparticles for Delivery of mRNA

Technology / Case number: #24662
Robert Langer / Allen Jiang / Sushil Lathwal / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Robocap

Technology / Case number: #24836J
Giovanni Traverso / Shriya Sruthi Srinivasan / Robert Langer / Amro Alshareef
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Modular MicroRNA Expression from Self-Replicating RNA (Replicons)

Technology / Case number: #25464
Ron Weiss / Tea Crnkovic
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Production of Stable Non-Polyadenylated RNAs

Technology / Case number: #15860
Jeremy Wilusz / Phillip Sharp
Technology Areas: Biotechnology / Drug Delivery
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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