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Microbial Production of 3,4-Dihydroxybutyrate (DHBA) and 3-Hydroxybutyrolactone (3-HBL) from Glucose

Technology / Case number: #14595
Kristala L Jones Prather / Collin Martin / Himanshu Dhamankar
Technology Areas: Chemicals & Materials / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Machine-Learning Optimized Proteins and Enzymes

Technology / Case number: #26015J
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Kaiyi Jiang / Matteo Di Bernardo / Zhaoqing Yan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Learning Algorithim for Ranking on Graph Data

Technology / Case number: #12236
Shivani Agarwal
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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Method for Image and Data Segmentation

Technology, Software / Case number: #13701H
H. Seung / Viren Jain / Srinivas Turaga
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living, Connected World
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Engineering Microbes and Metabolic Pathways for the Production of Ethylene Glycol from Xylose, Glucose, Carbohydrates and Renewable Resources

Technology / Case number: #15064
Deepak Dugar / Brian Pereira / Marjan De Mey / Jose Avalos / Gregory Stephanopoulos
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Brd4 as a Prognostic Indicator and Modulator of the Cell Response to DNA Damage

Technology / Case number: #15011
Scott Floyd / Michael Yaffe
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Cognitive Radio Method and Apparatus for Achieving Ad Hoc Interference Multiple Access Wireless Communication

Technology / Case number: #15918L
Rachel Learned / Nicholas Kaminski
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems
Impact Areas: Connected World
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Method for the Characterization and Differentiation of Material Surfaces Using Compound Responses of Mechanically Driven Cells

Technology / Case number: #17585J
Dick Yue / Roland Bouffanais / Xiaoying Zhu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Cellular Surface Engineering via Multilayered Polymer Nanostructures

Technology / Case number: #12846
Albert Swiston / Michael F Rubner / Robert Cohen / Darrell J Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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System for Portable Body Surface Acquisition

Technology / Case number: #17269
Luca Giancardo / Carlos Sanchez Mendoza / Tobias Hahn / Aurelien Bourquard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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Ultrasonic Method for Measuring Concentrations of Particles, Cells and Islets in Suspension

Technology / Case number: #11886J
Steven Africk / Clark Colton
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Use of Ranking Methods in Machine Learning to Prioritize Chemical Compounds for Drug Discovery

Technology / Case number: #14011
Shivani Agarwal
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living
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Tough, Thermoreversible Hydrogels from the Arrested Phase Separation of Elastin-Like Polypeptides: Simple, Injectable, Biocompatible Substrates for the Engineering of Load-Bearing Tissues

Technology / Case number: #17430
Bradley D. Olsen / Matthew Glassman / Reginald Avery
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Genomic Editing with Site- Specific Retrotransposons

Technology / Case number: #25220
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Justin Lim / Christopher Fell
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Data-Driven System for Optimal Vehicle Fleet Dimensioning and Real-Time Dispatching Based on Shareability Networks

Technology / Case number: #18459
Paolo Santi / Giovanni Resta / Carlo Ratti
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
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Multi-Space Building Control Optimization Based on Graph Learning and Reinforcement Learning

Technology / Case number: #25968
Jeremy Gregory / Daisy Green / Kevin Kircher / You Lin / Audun Botterud / Joe Higgins / Francis Selvaggio / Leslie Norford
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Connected World
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sEMG Derived Neural Network-Based Motion Prediction Exoskeleton

Technology / Case number: #25254
Ellen Roche / Bon Koo / Lonnie Grove Petersen
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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mRNA Subunit Vaccines for African Swine Fever

Technology / Case number: #25930
Junru Cui / Fangfeng Yuan / Jianzhu Chen
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulations for Stabilizing Lactobacillus and Bifidobacterium Strains

Technology / Case number: #25723J
Giovanni Traverso / Christina Karavasili / Matt Murphy / Samantha Bozorgzadeh / Mairead Heavey / Kimberley Biggs / Isaac Tucker
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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