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Dissolvable Microcarriers for Adherent Cell Culture

Technology / Case number: #22052JDE
Ee Xien Ng / Krystyn Van Vliet
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools
Impact Areas: Advanced Materials
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Methods of Enhancing the Survival of Introduced Genes and Organisms

Technology / Case number: #22105TE
Kevin Esvelt / Sarah Vitak
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Provably Secure Large Language Models

Technology / Case number: #25397J
Andrei Barbu / Abdulrahman Alabdulkareem / Christian Arnold / Juan Ignacio Cases Martin / Boris Katz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Advanced Materials
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Dataset Distillation using Random Feature Approximation

Technology / Case number: #24329
Daniela Rus / Alexander Amini / Ramin Hasani / Noel Loo
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML)
Impact Areas: Connected World
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TSV Qubit

Technology / Case number: #22218L
Jamie Kerman / William Oliver / Donna-Ruth Yost / Danna Rosenberg / Jonilyn Yoder / Wayne Woods / Mollie Schwartz / Cyrus Hirjibehedin / Justin Mallek / Thomas Hazard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Electronics & Photonics
Impact Areas: Advanced Materials
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Robert Langer / Ganesh Shankar
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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High-Throughput Screens for Exploring Biological Functions of Microscale Biological Systems

Technology / Case number: #19737JR
Paul Blainey / Navpreet Ranu
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
D.B.Jay Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Diagnosis of Malignancy Using Developmental Relationships and Machine Learning

Technology / Case number: #23356
Salil Garg / Enrico Moiso
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Computer Science / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Ingestible Chemical Energy Harvesting System with Extended Lifetime

Technology / Case number: #23174
Giovanni Traverso / Jason Li / So-Yoon Yang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Energy & Distribution / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Engineering a Swine Macro-Organ Colorectal Cancer Platform to Combat Transport-Induced Chemotherapy Resistance

Technology / Case number: #22864JQ
Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael F Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Data Driven Material Discovery System

Technology / Case number: #21835J
Wojciech Matusik / Michael Foshey / Timothy Erps / Wan Shou / Mina Lukovic / Klaus Stoll / Bernhard Von Vacano / Hanns-Hagen Goetzke / Mina Konakovic Lukovic
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Machine Learning for the Design of Cancer Vaccine Adjuvants

Technology / Case number: #21680J
Giovanni Traverso / Ameya Kirtane / Daniel Reker / Robert Langer / Lewis Scott Jones / Hyunjoon Kim / Netra Kamat
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Peggy Hsu / David Sykes / Frances Diehl
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Kevin Kauffman / James Kaczmarek / Asha Patel / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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