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Generation of Specialized, High-Value Cells and Tissues from Human Induced Pluripotent Stem Cells by Recapitulating Early Embryogenesis Using Gata Factor-Induced Endoderm

Technology, Tangible Property / Case number: #16205
Ron Weiss / Patrick Guye / Mohammad Reza Ebrahimkhani
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Method for High Efficiency in Vivo Gene Editing

Technology / Case number: #17117H
Wen Xue / Joseph Dorkin / Hao Yin / Tyler Jacks / Daniel Anderson
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Programmable Drug Delivery Profiles of Tumor-Targeted Bacteria

Technology / Case number: #15818H
Tal Danino / Sangeeta Bhatia
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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System for Portable Body Surface Acquisition

Technology / Case number: #17269
Luca Giancardo / Carlos Sanchez Mendoza / Tobias Hahn / Aurelien Bourquard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Sensing & Imaging
Impact Areas: Healthy Living
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High-Throughput Screening Metabolic Flux Biosensor

Technology / Case number: #16813JW
Jose Avalos / Gregory Stephanopoulos / Gerald Fink
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Epigenetic Mechanisms Re-Establish Access to Long-Term Memory After Neuronal Loss

Technology / Case number: #12467HPBJ
Weiping Tang / Andre Fischer / Li-Huei Tsai / Stephen Haggarty / Stuart Schreiber
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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In Vivo Targeting of T-Cells with Antibody- and Cytokine Conjugated Liposomes

Technology / Case number: #16405H
Yiran Zheng / Yuan Zhang / Brandon Kwong / Darrell J Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Use of Ranking Methods in Machine Learning to Prioritize Chemical Compounds for Drug Discovery

Technology / Case number: #14011
Shivani Agarwal
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living
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Tough, Thermoreversible Hydrogels from the Arrested Phase Separation of Elastin-Like Polypeptides: Simple, Injectable, Biocompatible Substrates for the Engineering of Load-Bearing Tissues

Technology / Case number: #17430
Bradley D. Olsen / Matthew Glassman / Reginald Avery
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Data-Driven System for Optimal Vehicle Fleet Dimensioning and Real-Time Dispatching Based on Shareability Networks

Technology / Case number: #18459
Paolo Santi / Giovanni Resta / Carlo Ratti
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Connected World, Advanced Materials
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Multi-Space Building Control Optimization Based on Graph Learning and Reinforcement Learning

Technology / Case number: #25968
Jeremy Gregory / Daisy Green / Kevin Kircher / You Lin / Audun Botterud / Joe Higgins / Francis Selvaggio / Leslie Norford
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Connected World
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sEMG Derived Neural Network-Based Motion Prediction Exoskeleton

Technology / Case number: #25254
Ellen Roche / Bon Koo / Lonnie Grove Petersen
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Industrial Engineering & Automation
Impact Areas: Advanced Materials
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Cystic Fibrosis Correction with Programmable Genomic Editing

Technology / Case number: #24666
Omar Abudayyeh / Jonathan S. Gootenberg / Matthew Yarnall / Christopher Fell
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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mRNA Subunit Vaccines for African Swine Fever

Technology / Case number: #25930
Junru Cui / Fangfeng Yuan / Jianzhu Chen
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermally-Gelling Injectable Hydrogel Composites for Therapeutic Delivery

Technology / Case number: #25878
Patrick Doyle / Talia Zheng
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Formulations for Stabilizing Lactobacillus and Bifidobacterium Strains

Technology / Case number: #25723J
Giovanni Traverso / Christina Karavasili / Matt Murphy / Samantha Bozorgzadeh / Mairead Heavey / Kimberley Biggs / Isaac Tucker
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Translating Text to, Merging, and Optimizing Graphical User Interface Tasks

Technology / Case number: #13972
Dina Katabi / Satchuthananthavale Branavan / Regina Barzilay / Nate Kushman / Martin Rinard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Connected World
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A Single-Walled Carbon Nano-Tube/Chitosan Hydrogel Array for the Label-Free, Optical Detection of Protein-Protein Interactions

Technology / Case number: #14201
Michael S. Strano / Jong Ho Kim / Paul Barone / Jin Ho Ahn / Nigel Reuel
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living
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A Device and a Method for Real-Time Dynamic Analysis and Guidance (RTAG) of On-Line Learning

Technology / Case number: #17389
Emery N Brown / Demba Ba / Anne Smith
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Connected World
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Compositions for Enhancing Esophageal Drug Retention and Absorption

Technology / Case number: #25238J
Giovanni Traverso / Christina Karavasili
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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