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Nucleic Acid-Conjugated Polymeric Nanoparticles for Gene Therapy

Technology / Case number: #23628JQ
Natalie Artzi / Pere Dosta Pons / Alexander M Cryer
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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A Machine Learning Platform for Diverse Applications in Drug Discovery and Delivery

Technology / Case number: #23916HM
Edward Stuart Boyden / Chi Zhang / Tay Won Shin
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science
Impact Areas: Healthy Living
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Method and Apparatus for Inferring Elevated Pulmonary Capillary Wedge Pressures from Single-Lead Electrocardiogram Telemetry Data

Technology, Software / Case number: #23955J
Daphne Schlesinger / Ridwan Alam / Eugene Pomerantsev / Collin M Stultz
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biomaterials & Bioelectronics / Biotechnology
Impact Areas: Healthy Living
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Adhesive, Injectable Hydrogels for Local Therapy Delivery to Brain Tumors

Technology / Case number: #24170JQ
Natalie Artzi / Michelle Dion / Dahis Daniel
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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System and Method for Automated Ovarian Follicular Monitoring

Technology / Case number: #19173PJ
Emery N Brown / Rose Faghih / Aaron Styer
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science
Impact Areas: Healthy Living
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  • Women's Health
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Stable and Efficient Cell Surface Coupling of Nanoparticles

Technology / Case number: #17836HQ
Yiran Zheng / Li Tang / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lipid Nanoparticles for Drug Delivery to Microglia in the Brain

Technology / Case number: #23156P
Li-Huei Tsai / Owen Fenton / Joel Blanchard / Robert Langer / Jason Andresen / Julia Bonner / William Ralvenius
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Interfacial Bioconjugation on Emulsion Droplets

Technology / Case number: #20314
Qifan Zhang / Timothy Manning Swager
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Advanced Materials
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All-Optical Holographic Implementation of Constant-Depth Quantum Circuits

Technology / Case number: #21655
Dirk R Englund / Donggyu Kim
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Sensing & Imaging
Impact Areas: Uncharted Frontiers, Advanced Materials
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Machine Learning for Accelerated IBFD Tuning

Technology / Case number: #22007L
Ken Kolodziej / Bradley Perry / Aidan Cookson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World, Advanced Materials
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Certified Control

Technology / Case number: #21653
Soonho Kong / Jonathan DeCastro / Dimitris Koutentakis / FengPing Angela Leong / Mike Wang / Nikos Gonzalez / Xin Zhang / Daniel Jackson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Industrial Engineering & Automation
Impact Areas: Sustainable Future, Connected World
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Joint Qubit Manipulation and Readout for Majorana-Based Quantum Information Processing

Technology / Case number: #20208
Liang Fu / Constantin Schrade
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Chemicals & Materials / Computer Science / Electronics & Photonics
Impact Areas: Uncharted Frontiers, Advanced Materials
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Antibody Mediated Delivery of Antigen to B Cell Follicles for Enhanced Humoral Response

Technology / Case number: #24727H
Aereas Aung / Darrell J Irvine
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Brain-Computer Interface for User's Visual Focus Detection

Technology / Case number: #20246
Alexandre Armengol Urpi / Sanjay Emani Sarma
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology
Impact Areas: Healthy Living, Uncharted Frontiers, Connected World
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Multi-Targeted, Tunable, Sustained Delivery of Drugs and Other Payloads to Charged Avascular Tissues

Technology / Case number: #21303
Yamini Krishnan / Alan Grodzinsky
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Distributed Training and Management of Al Powered Robots using Teleoperation via Virtual Spaces

Technology / Case number: #20397
Daniela Rus / Jeffrey Lipton / Aidan Fay / Changhyun Choi
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Computer Science / Industrial Engineering & Automation
Impact Areas: Uncharted Frontiers, Connected World
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Targeting Dendritic Cell Lectins with Glycosylated Particles Containing TLR Ligands Facilitates Efficient Immune Responses

Technology / Case number: #24570J
Laura L Kiessling / Valerie Lensch / M.G. Finn / Mohammad Murshid Alam / Robert Hincapie
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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RNA-Loaded Lipid Nanoparticle (LNP)

Technology, Tangible Property / Case number: #24973H
B.j. Kim / Darrell J Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Persistent Carbene Monolayers on Silicon Substrates

Technology / Case number: #18755
Jeremiah A. Johnson / Aleksandr Zhukhovitskiy
Technology Areas: Chemicals & Materials / Drug Delivery / Sensing & Imaging
Impact Areas: Advanced Materials
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DNA Virus Launched RNA Replicon System (VREP) for Prolonged and High Level Expression of Transgenes with High Precision Controls

Technology / Case number: #20866
Ron Weiss / Jacob Becraft / Jin Huh
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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