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A Handheld Closed-Loop Automatic Insulin Delivery System

Technology / Case number: #22018J
Giovanni Traverso / Hen Wei Huang / Sean You / Erin Raftery / Canchen Li
Technology Areas: Biotechnology / Communication Systems / Drug Delivery
Impact Areas: Healthy Living
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Genotype-Directed Local Delivery of Targeted Therapeutics at the Tumor Margin

Technology / Case number: #19863J
Giovanni Traverso / Ameya Kirtane / Daniel Cahill / Robert Langer / Ganesh Shankar
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Formulated, Biodegradable Polymeric Nanoparticles for Nucleic Acid Delivery to Non-Liver Targets

Technology / Case number: #19802
Kevin Kauffman / James Kaczmarek / Asha Patel / Luke Rhym / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Novel Ionizable Lipids Suitable For Lipid Nanoparticle Delivery of mRNA to Lung and Nasal Epithelium, As Well As Lung Endothelium

Technology / Case number: #23594Q
Luke Rhym / Allen Jiang / Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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New Ionizable Lipid Library Suitable for Multiple Organ Targeting Derived From High Throughput Combinatorial Synthesis and Screening

Technology / Case number: #23406
Bowen Li / Akiva Gordon / Idris Raji / Daniel Anderson
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single-Cell RNA Sequencing Using Click-Chemistry

Technology / Case number: #20396
D.B.Jay Mahat / Phillip Sharp
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Receptor Specific Peptides for Bcl-2 Family Anti-apoptotic Proteins

Technology / Case number: #20337J
Amy Keating / Gevorg Grigoryan / Justin Jenson / Vincent Xue / Jianfu Zhou
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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A Bioinspired Design of Self-Adjuvanted C3d-Fusion SARS-CoV-2 mRNA Vaccines

Technology / Case number: #23326
Robert Langer / Bowen Li / Allen Jiang / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Closed-Loop Intramuscular Motility Prosthesis, Submucosal Neuromodulation Device and Minimally Invasive Endoscopic Implantation Tool

Technology / Case number: #23258J
Polina Anikeeva / Giovanni Traverso / Shriya Sruthi Srinivasan / Robert Langer / Marc-Joseph Antonini
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Contact-Independent and High-Resistance Measurement of Electrical Conductance of a Thin Solid Film with a Nanoscale Sensor

Technology / Case number: #14921
Tamar Mentzel / Kenneth MacLean / Nirat Ray / Marc A Kastner
Technology Areas: Chemicals & Materials / Sensing & Imaging
Impact Areas: Advanced Materials
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Glucose-Responsive Glucagon Formulations for Closed-Loop Prophylactic Treatment of Hypoglycemia

Technology / Case number: #21838J
Giovanni Traverso / Robert Langer / Jason Li / Se Jun Lee
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Pants with Embedded Harness for Daily Use

Technology / Case number: #24380
Emily Kamienski / Karen Chen / Harry Asada
Technology Areas: Biotechnology / Chemicals & Materials
Impact Areas: Healthy Living
License

Catalytic Oxidation Reactors for the Removal of Low-Level Methane in Air

Technology / Case number: #24434
Desiree Plata / Asegun S Henry / Mehdi Pishahang / Qingzi Zhu / Rebecca Brenneis / Anastasios John Hart
Technology Areas: Chemicals & Materials / Environmental Engineering
Impact Areas: Climate Stabilization, Advanced Materials
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Hydrogen Selective Membranes

Technology / Case number: #24437
Rohit N Karnik / Randall Field / Aaron Persad / Chi Cheng / Lohyun Kim
Technology Areas: Chemicals & Materials
Impact Areas: Sustainable Future, Advanced Materials
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Method of Forming Topcoat for Patterning

Technology / Case number: #18405QJ
Priya Moni / Do Han Kim / Paul Nealey / Hyo Seon Suh / Karen Gleason
Technology Areas: Chemicals & Materials / Electronics & Photonics
Impact Areas: Advanced Materials
License

Cellular Backpacks for Drug Delivery Across the Blood-Brain Barrier

Technology / Case number: #18547J
Roberta Polak / Elena Batrakova / Matthew Haney / Yuling Zhao / Natalya Klyachko / Michael F Rubner / Robert Cohen
Technology Areas: Biotechnology / Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools
Impact Areas: Healthy Living
License

Spray-Coating Method with Particle Alignment Control

Technology / Case number: #18817J
Dayong Chen / Roberta Polak / Kenan Song / Khalid Askar / Michael F Rubner / Robert Cohen
Technology Areas: Chemicals & Materials
Impact Areas: Advanced Materials
License

Multiscale Porous High-Temperature Heat Exchanger

Technology / Case number: #21240J
Evelyn N. Wang / Lin Zhao / Bikramjit Bhatia / Arny Leroy / Kyle Wilke / Lenan Zhang / Xiangyu Li / Jeffrey Youngblood / Rodney Trice / Chad Wilson / Olivia Brandt / Rodrigo Guerra
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
License

Metal-Halogen Batteries using Immiscible Solvents

Technology / Case number: #21901V
Andres Badel / Fei Wang / Yet-Ming Chiang
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
License

P3MT/Horizontally-Aligned CNT Nanocomposite for Supercapcitor with High Areal Capacitance

Technology / Case number: #21425J
Brian L Wardle / Estelle Cohen / Yue Zhou / Xiaoxue Wang / Yosef (Yosi) Stein / Karen Gleason
Technology Areas: Chemicals & Materials / Energy & Distribution
Impact Areas: Advanced Materials
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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