Bradley L. Pentelute

Professor
Department
Department of Chemistry
Technology Areas
Chemicals & Materials: Catalysis & Synthesis / Drug Discovery and Research Tools: Genomics & Proteomics, Antibodies / Therapeutics: Proteins & Antibodies, Small Molecules, Nucleic Acids, Vaccines, Cell Based Therapy, Regenerative Medicine / Biotechnology: Synthetic Biology, DNA & RNA Editing / Computer Science: Bioinformatics
Impact Areas
Healthy Living, Uncharted Frontiers, Advanced Materials

Technologies

Translocation of Non-Natural Chemical Entities Through Anthrax Protective Antigen Pore

Technology / Case number: #15639J
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Gizem Akcay / R. Collier
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Rocco Policarpo
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Compounds, Compositions, and Methods of Macrocyclic Depsipeptide Antibiotics

Technology / Case number: #23104
Mohammad Movassaghi / Bradley L. Pentelute / Carly Schissel / Kyan D'Angelo
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Peptide-Encoded Libraries of Small Molecules for De Novo Drug Discovery

Technology / Case number: #23712
Bradley L. Pentelute / Nathalie Grob / Simon Roessler / Stephen Buchwald
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

An Efficient Bioconjugation Technology for Site-Selective Covalent Modification of Antibodies using an Engineered Affinity Peptide

Technology / Case number: #25358
Bradley L. Pentelute / Andrei Loas / Jacob Rodriguez / Heemal Dhanjee / Aurelie Rondon / Katsushi Kitahara
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Synthesis of Covalent Protein Dimers that can Inhibit MYC-Driven Transcription

Technology / Case number: #23305WJ
Bradley L. Pentelute / Isaac Klein / Carly Schissel / Sebastian Pomplun / Andrei Loas / Jacob Rodriguez / Muhammad Jbara / Ann Boija / Susana Hawken / Charles Li / Stephen Buchwald
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Uncharted Frontiers
License

Selective Metal-Mediated Arylation of Dichalcogenides in Biomolecules

Technology / Case number: #17814
Bradley L. Pentelute / Chi Zhang / Daniel Cohen / Stephen Buchwald
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Functionalization of Protective Antigen by Chemical Conjugation

Technology / Case number: #20802
Bradley L. Pentelute / Zeyu Lu
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Discovery of Self-Labeling Miniproteins

Technology / Case number: #18742
Bradley L. Pentelute / Ethan Evans
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Uncharted Frontiers, Advanced Materials
License

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