Richard D Braatz

Professor

Department
Department of Chemical Engineering
Technology Areas
Biotechnology: Biomanufacturing, Biomedical Devices & Systems, Synthetic Biology, Sensors & Monitoring / Therapeutics: Proteins & Antibodies, Nucleic Acids, Cell Based Therapy, Regenerative Medicine / Chemicals & Materials: Catalysis & Synthesis, Nanotechnology & Nanomaterials / Sensing & Imaging: Imaging, Optical Sensing / Industrial Engineering & Automation: Manufacturing & Equipment / Drug Discovery and Research Tools: Cell Culture / Drug Delivery: Vectors & Virus like Particles / Computer Science: Bioinformatics

Background and Education

Dr. Richard D. Braatz is the Edwin R. Gilliland Professor of Chemical Engineering at MIT, where he conducts research into advanced biopharmaceutical manufacturing systems. In this role, he leads process data analytics, mechanistic modeling, and control systems for several projects on campus, including those focused on monoclonal antibody, viral vaccine, and gene therapy manufacturing. Dr. Braatz received an M.S. and Ph.D. from the California Institute of Technology and was the Millennium Chair and Professor at the University of Illinois at Urbana-Champaign and a Visiting Scholar at Harvard University before moving to MIT.

Dr. Braatz has collaborated with more than 20 companies including Novartis, Pfizer, Merck, Bristol-Myers Squibb, Biogen, Amgen, Takeda, and Abbott Labs. Honors include the AIChE PD2M Award for Outstanding Contribution to QbD for Drug Substance, the AIChE Excellence in Process Development Research Award, the Technical Innovation Award from the International Society of Automation, and the IEEE Control Systems Society Transition to Practice Award. He has published over 200 papers and three books, including Fault Detection and Diagnosis in Industrial Systems. Dr. Braatz is a Fellow of IEEE, IFAC, AIChE, and AAAS and a member of the U.S. National Academy of Engineering.

Awards and Honors 

  • John R. Ragazzini Education Award | 2023
  • Elected to the National Academy of Engineering | 2019
  • AIChE Separation Division Innovation Award | 2019
  • Elected AIChE Fellow | 2018
  • Automatica Paper Prize | 2017
  • Excellence In Education Award, Int'l Society of Automation | 2015
  • AIChE Computing in Chemical Engineering Award | 2014
  • AIChE PD2M Award for Outstanding Contribution to QbD for Drug Substance | 2013
  • Technical Innovation Award, Int'l Society of Automation | 2013
  • Distinguished Lecturer, IEEE Control Systems Society | 2013
  • IEEE Control Systems Society Transition to Practice Award | 2011
  • Research Collaboration Award, Council for Chemical Research | 2009
  • Fellow, American Association for the Advancement of Science | 2008
  • Journal of Process Control Prize Paper Award (for theory/ methodology) | 2008
  • Journal of Process Control Prize Paper Award (for a survey) | 2008
  • Fellow, Int'l Federation of Automatic Control | 2008
  • Fellow, Institute of Electrical and Electronics Engineers | 2007
  • AIChE Excellence in Process Development Research Award | 2006
  • Antonio Ruberti Young Researcher Prize | 2005
  • IEEE Transactions on Control Systems Technology Outstanding Paper Award | 2005
  • CAST Outstanding Young Researcher Award, AIChE | 2005
  • Curtis W. McGraw Research Award, Engineering Research Council | 2004
  • CAST Directors' Award, AIChE | 2003
  • Ernest W. Thiele Lectureship, University of Notre Dame | 2001
  • Donald P. Eckman Award, American Automatic Control Council | 2000

Technologies

Weight Sensing

Technology / Case number: #26101
Richard D Braatz / Roberto Pisano / Steven Burcat / Alexander Slocum / Rohan Kadambi / Lorenzo Stratta / Bernhardt Trout
Technology Areas: Biotechnology / Computer Science
Impact Areas: Healthy Living
License

Convective Cooling Chamber

Technology / Case number: #26103
Richard D Braatz / Roberto Pisano / Steven Burcat / Alexander Slocum / Rohan Kadambi / Joshua Dittrich / Lorenzo Stratta / Bernhardt Trout
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Advanced Materials
License

An Approach for Enriching the Production of DNA Cargo Loaded AAV5 Capsids in Cells

Technology / Case number: #25585
Paul Barone / Richard D Braatz / Anthony Sinskey / Stacy Springs / Rui Wen Ou / Jacqueline Wolfrum / Prasanna Srinivasan / John Joseph
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Modular Continuous Lyophilizer

Technology / Case number: #26102J
Richard D Braatz / Roberto Pisano / Steven Burcat / Alexander Slocum / Rohan Kadambi / Joshua Dittrich / Bernhardt Trout
Technology Areas: Biotechnology / Industrial Engineering & Automation
Impact Areas: Connected World
License

Pupil Engineering Method to Enhance the Signal of the Real-time non-invasive Particle Size Distribution Probe in Powders and During Mixing, Drying, Blending, and Milling Processes

Technology / Case number: #24521
Allan S. Myerson / Richard D Braatz / Qihang Zhang / Zhen Guo / Ajinkya Pandit / George Barbastathis
Technology Areas: Chemicals & Materials / Industrial Engineering & Automation / Sensing & Imaging
Impact Areas: Advanced Materials
License

Thermal Imaging-based State Estimation of a Stefan Problem with Application to Cell Thawing

Technology / Case number: #24616
Allan S. Myerson / Richard D Braatz / Qihang Zhang / Moo Sun Hong / Ajinkya Pandit / Prakitr Srisuma / George Barbastathis
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
License

System and Method for Real-Time Determination of Particle Size Distributions in Dry Powders and During Mixing, Drying and Milling Processes using Machine Learning aided by Physics

Technology / Case number: #24090
Allan S. Myerson / Richard D Braatz / Qihang Zhang / Janaka Gamekkanda Gamaethige / George Barbastathis
Technology Areas: Chemicals & Materials / Sensing & Imaging
License

Preferential Crystallization of fullrAAVs in a Hanging Drop Crystallizer as an Alternative Method for Downstream Purification of rAAV-based Gene Therapies

Technology / Case number: #24870
Paul Barone / Richard D Braatz / Anthony Sinskey / Stacy Springs / Moo Sun Hong / Vivekananda Bal
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Optical Methods Level Sensor for Use in a Bioreactor

Technology / Case number: #19143
J. Christopher Love / Richard D Braatz / Craig Mascarenhas / Amos Lu
Technology Areas: Biotechnology
Impact Areas: Healthy Living
License

Model-based Control for Column-based Continuous Viral Inactivation of Biopharmaceuticals

Technology / Case number: #21959
Richard D Braatz / Amos Lu / Moo Sun Hong
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Sign up for technology updates

Sign up now to receive the latest updates on cutting-edge technologies and innovations.