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Crystalline and Amorphous Formulations Used to Deliver Anti-Fibrotic (and other) Compounds in Conjunction with Implanted Materials (Cells/Devices)

Technology / Case number: #18287J
Joshua Doloff / Shady Farah / Robert Langer / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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User-Friendly and Easily-Accessible Synthetic Hydrogels for Biomaterials Application

Technology / Case number: #20694
Owen Fenton / Robert Langer / Jason Andresen / Marion Paolini
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Thermo-Responsive, Inflammation-Targeting (TRIT) Hydrogel Formulations for Local Drug Delivery in Intestinal Inflammation

Technology / Case number: #19181J
Giovanni Traverso / Sufeng Zhang / Ashok Kakkar / Joshua Korzenik / Robert Langer
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living
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Microelectromechanical Systems for Acoustics

Technology / Case number: #19512
Apoorva Murarka / Vladimir Bulovic / Jeffrey Lang
Technology Areas: Biotechnology / Chemicals & Materials / Electronics & Photonics
Impact Areas: Healthy Living, Advanced Materials
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Hybrid Materials with Living Cells and Tough Hydrogels

Technology / Case number: #18548
Timothy K Lu / Xuanhe Zhao / Eleonore Tham / Xinyue Liu / Tzu-Chieh Tang
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Diagnostics / Therapeutics
Impact Areas: Healthy Living
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Cationic Lipidoids and Their Uses for Immunotherapy

Technology / Case number: #19803
Linxian Li / Yuxuan Huang / Lei Miao / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Luke Rhym / Bowen Li / Akiva Gordon / rajith manan / Jacob Witten / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Field Dependent Sensors from Redox Active Carbon Nanomaterials

Technology / Case number: #19822J
Suchol Savagatrup / Maggie He / Sibo Lin / Vera Schroeder / Xi-Xiang Zhang / Khaled Salama / Timothy Manning Swager
Technology Areas: Chemicals & Materials / Energy & Distribution / Sensing & Imaging
Impact Areas: Healthy Living
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Electrically-Triggered Degradation Of The Drug/Bacteria Chamber Covering

Technology / Case number: #24830J
Betar Gallant / Giovanni Traverso / Miguel Jimenez / Sean You / Seokkee Min / Rishabh Mittal / So-Yoon Yang / Adam Gierlach / James McRae / Kewang Nan / Yiyuan Yang / Emily Kolaya / Kyeongho Kim / Yeseul Jeon / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Energy & Distribution
Impact Areas: Healthy Living, Advanced Materials
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Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Single-shot 16-fold Expansion Microscopy (16ExM)

Technology / Case number: #24859MH
Edward Stuart Boyden / Laura L Kiessling / Tay Won Shin / Shiwei Wang / Yixi Liu / Harley Yoder
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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Soft Robotic, 3D-Printed Simulator of Heart Function and Disease

Technology / Case number: #25013J
Ellen Roche / Caglar Ozturk / Luca Rosalia / Jean Bonnemain / Sophie Wang / Christopher Nguyen / Debkalpa Goswami
Technology Areas: Biotechnology / Chemicals & Materials / Industrial Engineering & Automation
Impact Areas: Healthy Living
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Spatially Localized Gene Delivery of Adeno-Associated Viruses

Technology / Case number: #25055
Polina Anikeeva / Keisuke Nagao
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Ultrastructural Membrane Expansion Microscopy

Technology / Case number: #25088HM
Edward Stuart Boyden / Tay Won Shin
Technology Areas: Chemicals & Materials / Diagnostics / Sensing & Imaging
Impact Areas: Healthy Living
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Reconstituted Lipoprotein Particles to Rescue Lipid Defects in the Alzheimer's Brain

Technology / Case number: #25445P
Li-Huei Tsai / Rebecca Pinals
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Latent-Fluoride Containing Polymers for Triggered Degradation

Technology / Case number: #23066
Jeremiah A. Johnson / Peyton Shieh / Christopher Brown
Technology Areas: Chemicals & Materials
Impact Areas: Healthy Living, Advanced Materials
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Method of Enhanced Clearance of Uremic Toxins in Hemodialysis using Nanoporous Membranes

Technology / Case number: #21853
Rohit N Karnik / Aaron Persad / Chun Man Chow / Chi Cheng
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Microscale Photoacoustic Spectroscopy and Microscopy

Technology / Case number: #21078
Brian Anthony / Robin Singh / Anuradha Murthy Agarwal
Technology Areas: Biotechnology / Chemicals & Materials / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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