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Engineering DNA Assembly in Vivo and Knock Down of Gene Expression Using the Reverse Transcriptase Activity

Technology / Case number: #16593
Christopher Voigt / Johann Elbaz
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Single Wall Carbon Nanotubes as In Vivo Sensors

Technology / Case number: #16531
Michael S. Strano / Nigel Reuel / Thomas McNicholas / Nicole Iverson
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Engineered Probiotics for Urinary Cancer Diagnosis

Technology / Case number: #15881HJ
Tal Danino / Arthur Prindle / Jeff Hasty / Sangeeta Bhatia
Technology Areas: Biomaterials & Bioelectronics / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Methodology to Deconvolve Metabolic Heterogeneity

Technology / Case number: #25787J
Yunping Qiu / Irwin Kurland / Lillian Delacruz / Alison Ringel
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Branched Chain Fatty Acids Have Immune-Modulatory Effects

Technology / Case number: #25569P
Li-Huei Tsai / Lorenzo Bozzelli
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Micronutrient-Stabilizing Materials

Technology / Case number: #25722
Ana Jaklenec / Robert Langer / Linzixuan Rhoda Zhang / Xin Yang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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MMAF-Conjugated Layer-by-Layer Nanoparticles for Local Glioblastoma Treatment

Technology / Case number: #25705
Michael Marand / Nicholas Lamson / Andrew Pickering / Paula Hammond
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Protein Retrosplicing Enabled by a Double Ligation Reaction

Technology / Case number: #15368
Bradley L. Pentelute / Xiaoli Liao / Amy Rabideau / Jingjing Ling / Rocco Policarpo
Technology Areas: Computer Science / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Identification of Mitochondrial GABA Transporter

Technology / Case number: #26187
Matthew Vander Heiden / Samuel Block
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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Fluorescent Metal-Based Nitric Oxide Sensor for Live Cells

Technology / Case number: #11806
Mi Hee Lim / Stephen J Lippard
Technology Areas: Chemicals & Materials / Sensing & Imaging / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Self-Assembling Peptides Incorporating Modifications and Methods of Use Thereof

Technology / Case number: #12321XE
Akihiro Horii / Fabrizio Gelain / Xiumei Wang / Shuguang Zhang
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Metakaryocides for Treatment of Cancers and Other Diseases with Metakaryotic Stem Cells

Technology / Case number: #15279
Elena Gostjeva / William Thilly
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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High Throughput Isolation of Antigen-Specific Antibodies and Cells

Technology / Case number: #16927J
Han Wei Hou / Aniruddh Sarkar / Galit Alter / Jongyoon Han
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
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One-Step Protein Analysis Using Slanted Nanofilter Array

Technology / Case number: #17391
Sung Ko / Jongyoon Han
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Single Molecule Peptide Sequencing in Polymer Gel

Technology / Case number: #25381HM
Edward Stuart Boyden / Chi Zhang / Camille Mitchell / Hao Wang
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Machine-Learning Optimized Proteins and Enzymes

Technology / Case number: #26015J
Omar Abudayyeh / Jonathan S. Gootenberg / Lukas Villiger / Kaiyi Jiang / Matteo Di Bernardo / Zhaoqing Yan
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Diminished Proteolytic Shedding of Receptor Tyrosine Kinases Mediates MEK Inhibitor Resistance in Triple-Negative Breast Cancer

Technology / Case number: #16742
Aaron Meyer / Miles Miller / Madeleine Oudin / Linda Griffith / Douglas Lauffenburger / Frank Gertler
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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  • Women's Health
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Extended Transient Transfection by Repeated Delivery of RNA

Technology / Case number: #13415
Matthew Angel / Mehmet Yanik
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Surface Binding of Nanoparticles-Based Drug Delivery to Tissue

Technology / Case number: #15731
Rohit N Karnik / Cliff Wong / Ambika Bajpayee / Alan Grodzinsky / Moungi G Bawendi
Technology Areas: Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Nanoparticle Technology for Immune Response Against Small and Macromolecules-Method of Preparation and Uses Thereof

Technology / Case number: #13399J
Frank Alexis / Pamela Basto / Ulrich Von Andrian / Elliot Moseman / Matteo Iannacone / Jinjun Shi / Elena Tonti / Robert Langer / Omid Farokhzad
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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