Darrell J Irvine

Professor, Mat'l Sci & Eng and Biological Eng
Department
David H Koch Institute for Integrative Cancer Res
Technology Areas
Chemicals & Materials: Nanotechnology & Nanomaterials, Polymers, Catalysis & Synthesis, Metals / Drug Delivery: Microparticles & Nanoparticles, Vectors & Virus like Particles / Therapeutics: Cell Based Therapy, Proteins & Antibodies, Vaccines, Nucleic Acids, Small Molecules / Drug Discovery and Research Tools: Antibodies, Genomics & Proteomics, Cell Interrogation / Biotechnology: Synthetic Biology, Biomedical Devices & Systems, Sensors & Monitoring, DNA & RNA Editing, Cell Separation / Diagnostics: Assays, Imaging Agents / Biomaterials & Bioelectronics: Health Monitoring
Impact Areas
Healthy Living, Advanced Materials, Uncharted Frontiers

Technologies

Scalable and High throughput Assembly of Layer-by-Layer Nanoparticles

Technology / Case number: #25554H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery
Impact Areas: Healthy Living, Advanced Materials
License

Methods to Specifically Profile Protease Activity at Lymph Nodes

Technology / Case number: #18619H
Andrew Warren / Jaideep Dudani / Naveen Mehta / Sangeeta Bhatia / Darrell J Irvine / Karl Dane Wittrup
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
License

Lipid Anchorage of Cytokines onto Layer-by-Layer Nanoparticles

Technology / Case number: #25070H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Cell-Surface Anchored Cytokine Therapy

Technology, Tangible Property / Case number: #25245H
Luciano Santollani / Darrell J Irvine / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Optimized Alum-Anchored HIV Env Immunogens

Technology / Case number: #24972HJ
Kristen Rodrigues / Christopher Cottrell / Jon Steichen / William Schief / Darrell J Irvine
Technology Areas: Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

1. Methods for in Vitro Evolution of Constructs Derived from Viruses. 2. Five Mutations Derived from the in Vitro Evolution. 3. Seventeen constructs from the five mutations.

Technology / Case number: #20395H
Ron Weiss / Yingzhong Li / Darrell J Irvine
Technology Areas: Biotechnology / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
License

Immunostimulatory Nanoparticle Adjuvants

Technology / Case number: #20798HJ
Murillo Silva / Yu Kato / Shane Crotty / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Programmable Immunostimulation with Structured DNA Nanoparticles

Technology / Case number: #24273H
Mark Bathe / Remi Veneziano / Rebecca Du / Tyson Moyer / Eike-Christian Wamhoff / Benjamin Read / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Single-Dose Combination Immunotherapy Augments Responses to Checkpoint Blockades for the Treatment of Cancer

Technology / Case number: #21150H
Chensu Wang / Darrell J Irvine / Karl Dane Wittrup
Technology Areas: Therapeutics
Impact Areas: Healthy Living
License

Uses of Amphiphiles in Immune Cell Therapy and Compositions Therefore

Technology / Case number: #21411H
Peter DeMuth / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

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