Darrell J Irvine

Professor, Mat'l Sci & Eng and Biological Eng
Department
David H Koch Institute for Integrative Cancer Res
Technology Areas
Chemicals & Materials: Nanotechnology & Nanomaterials, Polymers, Catalysis & Synthesis, Metals / Drug Delivery: Microparticles & Nanoparticles, Vectors & Virus like Particles / Therapeutics: Cell Based Therapy, Proteins & Antibodies, Vaccines, Nucleic Acids, Small Molecules / Drug Discovery and Research Tools: Antibodies, Genomics & Proteomics, Cell Interrogation / Biotechnology: Synthetic Biology, Biomedical Devices & Systems, Sensors & Monitoring, DNA & RNA Editing, Cell Separation / Diagnostics: Assays, Imaging Agents / Biomaterials & Bioelectronics: Health Monitoring
Impact Areas
Healthy Living, Advanced Materials, Uncharted Frontiers

Technologies

STING Agonist Delivery by Lipid Nanodiscs for Tumor Immunotherapy

Technology / Case number: #21441HJ
Eric Dane / Masanori Okaniwa / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Intra-Tumoral Injection of Cytotoxic Chemotherapy-Treated Tumor Cells in Combination with Systemic Immune Checkpoint Blockade for Cancer Treatment

Technology / Case number: #21498H
Ganapathy Sriram / Lauren Milling / Darrell J Irvine / Michael Yaffe
Technology Areas: Diagnostics / Therapeutics
Impact Areas: Healthy Living
License

Control Replication and Transcription of Self-Replicating RNA in Responses to Small Molecule TMP

Technology / Case number: #22331H
Ron Weiss / Yingzhong Li / Jan Lonzaric / Parisa Yousefpour / Darrell J Irvine
Technology Areas: Biotechnology / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
License

Synergistic Combination of Alum and SMNP Vaccine Adjuvants

Technology / Case number: #23626H
Kristen Rodrigues / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Engineered Alum-binding SARS-CoV-2 Immunogens

Technology / Case number: #23632H
J. Christopher Love / Neil Dalvie / Sergio Rodriguez / Kristen Rodrigues / Darrell J Irvine
Technology Areas: Biotechnology / Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Stable and Efficient Cell Surface Coupling of Nanoparticles

Technology / Case number: #17836HQ
Yiran Zheng / Li Tang / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
License

Slow Delivery of Antigen and Adjuvant Plus A Delayed Boost for Unexpected Immunogenicity

Technology / Case number: #23762HJ
Shane Crotty / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Intranasal amphiphile-protein conjugate vaccine

Technology / Case number: #23991H
Brittany Hartwell / Darrell J Irvine
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

Universal Redirection of Chimeric Antigen Receptor T Cells Against Solid Tumors via Tumor Cell Membrane-Inserting CAR Ligands

Technology / Case number: #24270H
Angela Zhang / Laura Chen / Alexander Hostetler / Darrell J Irvine
Technology Areas: Biotechnology / Therapeutics
Impact Areas: Healthy Living
License

Controlled Lipid Self-Assembly for Scalable Manufacturing of Next-Generation Immune Stimulating Complexes

Technology / Case number: #24582H
Ivan Pires / Darrell J Irvine / Paula Hammond
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
License

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