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Small Molecules Suppressors of APOE Gene Expression and Cerebral Vascular Amyloid Pathology

Technology / Case number: #22991P
Li-Huei Tsai / Joel Blanchard
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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Lung-Cancer Specific T Cell Dysfunction

Technology / Case number: #23004
J. Christopher Love / Stefani Spranger / Brendan Horton / Duncan Morgan / Karl Dane Wittrup
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Nanosensors for Detecting and Imaging of Cancer Metastasis

Technology / Case number: #20490H
Liang Hao / Sangeeta Bhatia
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living
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Autocatalytic Base Editing for RNA-Responsive Translational Control

Technology / Case number: #24552YJ
James Collins / Raphael Gayet / Katherine Ilia / Shiva Razavi / Nathaniel Tippens / Kehan Zhang / Xiaoyu Chen / Jonathan C. Chen / Makoto Lalwani
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Compounds, Compositions, and Methods of Macrocyclic Depsipeptide Antibiotics

Technology / Case number: #23104
Mo Movassaghi / Bradley L. Pentelute / Carly Schissel / Kyan D'Angelo
Technology Areas: Chemicals & Materials / Therapeutics
Impact Areas: Healthy Living
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Multi-Input miRNA Sensing with Constitutive ERNs to Regulate Multi-Output Gene Expression in Mammalian Cells

Technology / Case number: #23123
Ron Weiss / Deepak Mishra / Erez Pery / Wenlong Xu / Lei Wang
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Heme-binding Small Peptide

Technology / Case number: #23132
Graham Walker / Siva Sankari Iyer Mani Sankaran / Vigneshbabu Musuri Periasamy
Technology Areas: Therapeutics
Impact Areas: Healthy Living
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System and Method for Automated Ovarian Follicular Monitoring

Technology / Case number: #19173PJ
Emery N Brown / Rose Faghih / Aaron Styer
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Biotechnology / Communication Systems / Computer Science
Impact Areas: Healthy Living
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  • Women's Health
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Stable and Efficient Cell Surface Coupling of Nanoparticles

Technology / Case number: #17836HQ
Yiran Zheng / Li Tang / Darrell J Irvine
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Lipid Nanoparticles for Drug Delivery to Microglia in the Brain

Technology / Case number: #23156P
Li-Huei Tsai / Owen Fenton / Joel Blanchard / Robert Langer / Jason Andresen / Julia Bonner / William Ralvenius
Technology Areas: Chemicals & Materials / Drug Delivery / Therapeutics
Impact Areas: Healthy Living
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Redox-Electrodes for Electrochemically-Controlled Bio-Macromolecule Interaction: Bio-Separations, Heterogeneous Enzyme Immobilization, Protein Purification and Sensing, Among Others

Technology / Case number: #18540
T. Alan Hatton / Xiao Su
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Protein-Surfactant-Monomer/Polymer Blends for Protein-Based Elastomers

Technology / Case number: #19861
Bradley D. Olsen / Wui Yarn Chan
Technology Areas: Biotechnology / Chemicals & Materials / Environmental Engineering
Impact Areas: Sustainable Future, Advanced Materials
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Microbial Production of Renewable Glycolate

Technology / Case number: #18161
Brian Pereira / Zheng-Jun Li / Gregory Stephanopoulos
Technology Areas: Biotechnology / Environmental Engineering
Impact Areas: Sustainable Future
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TRAV-005 (Needles) 62/795,857

Technology / Case number: #22144J
Selim Olcum / Robert Kimmerling / David Weinstock / Scott Manalis
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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A Modified Viscoelastic Assay Rapidly Unmasks Pathological Fibrinolysis Phenotypes in a Wide Spectrum of Human Diseases

Technology / Case number: #19496J
Christopher Barrett / Ernest Moore / Hunter Moore / Michael Yaffe
Technology Areas: Biotechnology / Diagnostics
Impact Areas: Healthy Living
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Strain and Bioprocess Engineering for High Lipid Production

Technology / Case number: #18140
Kangjian Qiao / Peng Xu / Gregory Stephanopoulos
Technology Areas: Biotechnology / Environmental Engineering
Impact Areas: Sustainable Future
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Flat Pack Face Shield

Technology / Case number: #22311
Jonathan Hunt / Angelina Jay / Seth Avecilla / Robyn Goodner / Martin Luther Culpepper
Technology Areas: Biotechnology
Impact Areas: Healthy Living, Connected World
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X-Ray Nanoscope

Technology / Case number: #21383
Rajiv Gupta / Richard Lanza / Berthold Klaus Paul Horn / Akintunde Ibitayo Akinwande / George Barbastathis
Technology Areas: Biotechnology / Chemicals & Materials / Diagnostics
Impact Areas: Healthy Living, Advanced Materials
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Methods of Multiplexing CRISPR

Technology / Case number: #21646TE
Kevin Esvelt / Mariah Savoie (Avila) / Ashton Strait / Emma Chory
Technology Areas: Biotechnology / Chemicals & Materials / Computer Science
Impact Areas: Healthy Living
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Rapid Droplet-Based Systems for Antibody Drug Discovery

Technology / Case number: #23890J
Brandon DeKosky / Matias Gutierrez Gonzalez / Cheng-yu Chung / Ahmed Fahad / Nicoleen Boyle / Shuyan Jin
Technology Areas: Biotechnology / Diagnostics / Drug Discovery and Research Tools / Sensing & Imaging
Impact Areas: Healthy Living
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The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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