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Nucleotide Depletion as Differentiation Therapy in the Treatment of Cancer

Technology / Case number: #21131J
Matthew Vander Heiden / Peggy Hsu / David Sykes / Frances Diehl
Technology Areas: Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Tissue Platform and Machine Learning Algorithm for Drug-Drug Transporter Interaction Discovery

Technology / Case number: #21883J
Giovanni Traverso / Yunhua Shi / Vance Soares / Daniel Reker / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Biodegradable Polymers for Messenger RNA Delivery to the Lung

Technology / Case number: #19314
Kevin Kauffman / James Kaczmarek / Asha Patel / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Structure-Guided Chemical Modification of Guide RNA and its Applications

Technology / Case number: #19175V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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sgRNA Chemical Modification for Efficient Gene Editing

Technology / Case number: #17805V
Hao Yin / Robert Langer / Daniel Anderson
Technology Areas: Biotechnology / Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Relativistic Statistical Arbitrage

Technology / Case number: #14247J
Cameron E Freer / Alexander Wissner-Gross
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Microbial Production of Alpha-Substituted 3-Hydroxy Acids from Glucose

Technology / Case number: #25163
Kristala L Jones Prather / K'yal Bannister
Technology Areas: Biotechnology / Drug Discovery and Research Tools
Impact Areas: Healthy Living
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Decoding via Guessing Noise

Technology / Case number: #20169J
Jiange Li / Kenneth Duffy / Muriel Medard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Uncharted Frontiers
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Decoding by Guessing Noise II

Technology / Case number: #20215J
Kenneth Duffy / Muriel Medard
Technology Areas: Artificial Intelligence (AI) and Machine Learning (ML) / Communication Systems / Computer Science
Impact Areas: Connected World, Advanced Materials
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Ionizable Lipids for Messenger RNA Delivery

Technology, Tangible Property / Case number: #24861
Jacob Witten / Idris Raji / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Delivery / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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A Generalizable, High-Throughput Method to Rapidly add Chemical Moieties to a Small Molecule Library

Technology / Case number: #22196J
Angela Koehler / Brice Curtin / Jasmin Kruell / Catherine Henry / Sebastian Pomplun / Christina Woo / Chia-fu Chang
Technology Areas: Biotechnology / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living
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Gastric Residence Electronics

Technology / Case number: #20092J
Giovanni Traverso / Yong Lin Kong / Robert Langer
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living
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Electrically Driven Light-Emitting Tunnel Junctions

Technology / Case number: #18393
Farnaz Niroui / Thomas Mahony / Vladimir Bulovic / Jeffrey Lang
Technology Areas: Communication Systems / Sensing & Imaging
Impact Areas: Advanced Materials
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Synthesis of Ester, Carbonate, and Carbamate-derived Novel Biodegradable Ionizable Lipids from Methyl Ricinoleate or Methyl 12-Hydroxystearate and its Applications

Technology / Case number: #23381Q
Luke Rhym / Bowen Li / Akiva Gordon / rajith manan / Jacob Witten / Daniel Anderson
Technology Areas: Chemicals & Materials / Drug Discovery and Research Tools / Therapeutics
Impact Areas: Healthy Living, Advanced Materials
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Optical Network Switch for Dynamically Reconfigurable Multicast Topologies

Technology / Case number: #19503L
Dirk R Englund / Gregory Steinbrecher
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Base Station Ordering Technique (BoLT) for Localization in Dense Cellular Networks

Technology / Case number: #19869J
Moe Win / Wenhan Dai / Mohamed-Slim Alouini / Hesham ElSawy
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Data-Driven Angular Jitter Estimator for Lidar

Technology / Case number: #21433L
Eric Statz / Eric Phelps / Charles Primmerman
Technology Areas: Communication Systems / Computer Science
Impact Areas: Healthy Living, Advanced Materials
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Dual Polarized Notch Antenna Having Low Profile Stripline Feed

Technology / Case number: #21017L
Glenn Brigham
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Fiber Based RF Phased-Array Antennas

Technology / Case number: #21616L
Alexander Stolyarov / Sivasubramaniam Yegnanarayanan / Lauren Cantley / Alan Fenn
Technology Areas: Communication Systems / Computer Science
Impact Areas: Connected World
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Secure and Stable Wireless Communication for an Ingestible Device

Technology / Case number: #25143J
Giovanni Traverso / Adam Gierlach / James McRae / Yeseul Jeon / Ian Ballinger / Anantha Chandrakasan
Technology Areas: Biomaterials & Bioelectronics / Biotechnology / Communication Systems
Impact Areas: Healthy Living, Connected World
License

The technologies listed represent a selection of the MIT intellectual property protected by the TLO.

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